HSPA5, CT (HSPA5, GRP78, 78kD glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70kD protein 5, Immuno

Affinity Purified Purified by Protein A affinity chromatography.

HSPA5 protein

HSPA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-587 amino acids from the C-terminal region of human HSPA5.

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Polyclonal

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Human

Anti -HSPA5, CT (HSPA5, GRP78, 78kD glucose-regulated protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70kD protein 5, Immunoglobulin heavy chain-binding protein)

3309

P11021 [Other Products]