HRP Anti-delta 1 Catenin/CAS antibody [EPR357(2)]

HRP

Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed : 14610055, PubMed : 20371349). Promotes localization and retention of DSG3 at cell-cell junctions, via its interaction with DSG3 (PubMed : 18343367). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed : 10207085, PubMed : 20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed : 17344476).

Rabbit

Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

HRP兔单克隆抗体[EPR357(2)] to delta 1 Catenin/CAS

IgG

EPR357(2)

单克隆

Protein A purified

Liquid

细胞生物学

Antibody Labelling, Target Binding Affinity

The mouse recommendation is based on the WB results. We do not guarantee IHC-P for mouse.

KIAA0384, CTNND1, Catenin delta-1, Cadherin-associated Src substrate, p120 catenin, p120(cas), CAS, p120(ctn)

pH: 7.40Preservative: 0.1% Proclin 300 SolutionConstituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS

O60716