APC Anti-FXYD3 antibody [EPR17160]

Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell (PubMed : 17077088). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (PubMed : 21454534). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (PubMed : 7836447).. Isoform 1. Decreases the apparent K+ and Na+ affinity of the sodium/potassium-transporting ATPase over a large range of membrane potentials.. Isoform 2. Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials.

Rabbit

Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

APC兔单克隆抗体[EPR17160] to FXYD3

IgG

EPR17160

单克隆

Protein A purified

0.5 mg/mL 本产品的浓度可能与批次相关

Liquid

癌症

Target Binding Affinity, Antibody Labelling

MAT8, PLML, FXYD3, FXYD domain-containing ion transport regulator 3, Chloride conductance inducer protein Mat-8, Mammary tumor 8 kDa protein, Phospholemman-like, Sodium/potassium-transporting ATPase subunit FXYD3

pH: 7.40Preservative: 0.02% Sodium azideConstituents: 98% PBS, 1% BSA

Q14802