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产品介绍
产品介绍
产品信息
荧光素标记
HRP
抗原名称
Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed : 10722669, PubMed : 12527552, PubMed : 12590919, PubMed : 16214850, PubMed : 21795683, PubMed : 9396714, PubMed : 9478986). Functions as a Na(+)-independent, passive transporter (PubMed : 9478986). Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine (PubMed : 10722669, PubMed : 12527552, PubMed : 12590919, PubMed : 16214850, PubMed : 21795683, PubMed : 9396714, PubMed : 9478986). Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil) (PubMed : 16214850, PubMed : 21795683). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites (PubMed : 12527552). Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier (PubMed : 23639800). Mediates both the influx and efflux of hypoxanthine in skeletal muscle microvascular endothelial cells to control the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production (By similarity).. Isoform 3. Non functional nucleoside transporter protein for adenosine or thymidine transport. Does not express on cell membrane.
宿主
Rabbit
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
简单描述
HRP兔单克隆抗体[EPR11674] to ENT2
商品描述
Rabbit Recombinant Monoclonal ENT2 antibody - conjugated to HRP.
同种型
IgG
克隆号
EPR11674
克隆类别
单克隆
纯度
Protein A purified
浓度
0.5 mg/mL 本产品的浓度可能与批次相关
形式
Liquid
研究领域
免疫学和肿瘤学
应用
实验应用
Antibody Labelling, Target Binding Affinity
目标/特异性
May be unsuitable with mouse in WB.
背景
别名
DER12, ENT2, HNP36, SLC29A2, Equilibrative nucleoside transporter 2, hENT2, 36 kDa nucleolar protein HNP36, Delayed-early response protein 12, Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, Solute carrier family 29 member 2, Equilibrative NBMPR-insensitive nucleoside transporter
研究领域
Signal Transduction Protein Trafficking Nuclear Import / Export
制备和贮存
存储溶液
pH: 7.40Preservative: 0.1% Proclin 300 SolutionConstituents: 30% Glycerol (glycerin, glycerine), 1% BSA, 68% PBS
保存方式
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark.
数据库链接
UniProt ID
Q14542
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