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Recombinant Human ErbB3 / HER3 protein (Fc Chimera) (Active)

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产品介绍
产品介绍
产品信息
抗原名称
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed : 20682778). May also be activated by CSPG5 (PubMed : 15358134). Involved in the regulation of myeloid cell differentiation (PubMed : 27416908).

商品描述
Recombinant Human ErbB3 / HER3 protein (Fc Chimera) (Active) is a Human Fragment protein, in the 20 to 643 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, HPLC, MS.

应用
实验应用
SDS-PAGE, MS, HPLC

背景
别名
HER3, ERBB3, Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3

数据库链接
UniProt ID
P21860&&P21860

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