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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated

纯化方式
Protein A

抗原名称
Smad4

宿主
Rabbit

免疫原
Synthetic Peptide

同种型
IgG

克隆号
SDT-168-67

浓度
0.5 mg/ml

性状
Liquid

缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

产品类型
Recombinant mAb

应用
实验应用
WB、IP、ChIP

反应种属
Hu、Ms、Rt

预测反应种属
Bv, Pg

稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
1:1000IP
1:50IHC-P
ICC
IF
mIHC
ChIP
1:20
背景
别名
Mothers against decapentaplegic homolog 4; MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; hSMAD4

背景
SMAD (mothers against decapentaplegic homologs) molecules are the core components in TGF-β signaling pathway. TGF-β binding to its receptor induces phosphorylation and activation of receptor-regulated SMADs (R-SMADs), SMAD2 and SMAD3, which subsequently associate with their partner SMAD4 and translocate from cytoplasm to nucleus. Formation of R-SMAD–SMAD4 complexes is essential in signaling of most TGF-β family members.

细胞定位
Cytoplasm、Nucleus

制备和贮存
保存方式
12 months from date of receipt / reconstitution, -20 °C as supplied
数据库链接
Accession
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