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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated

氨基酸序列
Gln20-Thr417, with C-terminal 8*His

分子量
47-53kDa (Reducing)

纯度
>95% by SDS-PAGE

内毒素水平
<0.1EU/μg

性状
Lyophilized Powder

表达系统
HEK293

缓冲体系
PBS, pH7.4

标签
His Tag

种属
Mouse

电泳JSON
[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/product.imager.attribute/0/57243aea-2d81-4981-9216-9f9890bc3779.png","description":"1μg (R: reducing condition, N: non-reducing condition)."}]

背景
别名
SERPINF1, Serpin F1, PEDF, PIG35, EPC-1

背景
Human SERPINF1 gene codes for pigment epithelium-derived factor, a secreted glycoprotein and member of the SERPIN superfamily. Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF has affinity for PEDF-receptor (PEDF-R), a membrane-linked lipase encoded by the PNPLA2 gene. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties.

制备和贮存
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
文献
文献
1.Published online 2022 Feb 15.

数据库链接
Accession
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