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FITC Mouse Anti-Human/Mouse Granzyme B Antibody (S-2865)
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对比
咨询反应种属：
Hu、Ms
来源宿主：
Mouse
产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Protein G
抗原名称
Granzyme B
宿主
Mouse
同种型
IgG1,k
克隆号
S-2865
浓度
0.2 mg/ml
性状
Liquid
缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
产品类型
Mouse mAb
应用
实验应用
ICFCM
反应种属
Hu、Ms
稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
IP
IHC-P
ICC
IF
ICFCM
5μl per million cells in 100μl volumeFCM
mIHC
ChIP
背景
别名
C11; CTLA-1; Cathepsin G-like 1 (CTSGL1); Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease); Fragmentin-2; CGL1; CSPB; CTLA1; GRB; GZMB
背景
Granzyme B is a 32~kDa serine protease stored in the cytolytic granules of cytotoxic T lymphocytes and natural killer cells, whose immune function centers on perforin-assisted translocation into target cells where it directly cleaves and activates pro-apoptotic substrates such as procaspase-3, Bid and PARP, thereby igniting both caspase-dependent and caspase-independent mitochondrial apoptosis pathways to eliminate virus-infected or malignant cells.
细胞定位
Secreted
制备和贮存
保存方式
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
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