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产品信息
荧光素标记
Unconjugated
纯化方式
Protein A
宿主
Rabbit
免疫原
Synthetic Peptide
同种型
IgG
克隆号
S-668-119
浓度
0.5 mg/ml
性状
Liquid
缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
产品类型
Recombinant mAb
应用
实验应用
WB、IHC-P
反应种属
Hu
稀释度
WB
1:1000IHC-P
1:500
背景
别名
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
背景
CD46 is a type I membrane protein and is a regulatory part of the complement system. It has cofactor activity for inactivation (through cleavage) of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. It may also be involved in the fusion of the spermatozoa with the oocyte during fertilization. Recently, CD46 has emerged as a promising target for the treatment of both adenocarcinoma and neuroendocrine types of metastatic castration-resistant prostate cancer (mCRPC).
细胞定位
Membrane
制备和贮存
保存方式
12 months from date of receipt / reconstitution, -20 °C as supplied
数据库链接
Accession
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