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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated

纯化方式
Protein A

抗原名称
pro Caspase-1 + p10 + p12

宿主
Rabbit

免疫原
Synthetic Peptide

同种型
IgG

克隆号
S-2307-17

浓度
0.5 mg/ml

性状
Liquid

缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

产品类型
Recombinant mAb

应用
实验应用
WB、IHC-P

反应种属
Hu、Ms、Rt

稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
1:1000-1:2000IP
IHC-P
1:500ICC
IF
ICFCM
FCM
mIHC
ChIP
背景
别名
Caspase-1; CASP-1; Interleukin-1 beta convertase (IL-1BC); Interleukin-1 beta-converting enzyme (ICE; IL-1 beta-converting enzyme); p45; IL1BC; IL1BCE; CASP1

背景
Pro Caspase-1 is a 45 kDa inactive zymogen that, upon assembly of the canonical inflammasome, undergoes autoproteolysis between the p20 and p10 subunits, releasing an N-terminal CARD domain, the p20 subunit, and the p10 subunit; the resulting heterotetramer of two p20 and two p10 chains (often described as p20-p10 plus the additional p12 peptide that can remain non-covalently associated) forms the active caspase-1 protease, which subsequently cleaves pro-IL-1β and pro-IL-18 to drive inflammatory responses.

细胞定位
Cytoplasm、Cell membrane

制备和贮存
保存方式
12 months from date of receipt / reconstitution, -20 °C as supplied
数据库链接
Accession
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