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Invivo anti-mouse VEGFR-2 Recombinant mAb

Invivo anti-mouse VEGFR-2 Recombinant mAb

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纯度:
>95% (Determined by SDS-PAGE)
反应种属:
Ms
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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
纯化方式
Protein G
宿主
Rat
同种型
Rat IgG1,k
克隆号
DC101
纯度
>95% (Determined by SDS-PAGE)
内毒素水平
<1EU/mg
浓度
5 mg/ml
性状
Liquid
缓冲体系

PBS pH7.4, containing no preservative

产品类型
Rat mAb
应用
实验应用
WB、in vivo blocking of VEGF/VEGFR-2 signaling、in vitro blocking of VEGFR signaling
反应种属
Ms
稀释度
  • WB

    1:500
背景
别名
Vascular endothelial growth factor receptor 2, Fetal liver kinase 1 (FLK-1), Kinase NYK, Protein-tyrosine kinase receptor flk-1, CD309, Kdr, Flk-1, Flk1
背景

VEGFR-2 protein, also known as Vascular Endothelial Growth Factor Receptor 2 (VEGFR2 or KDR), is a crucial type III receptor tyrosine kinase that plays a pivotal role in regulating angiogenesis, vascular development, permeability, and embryonic hematopoiesis. Specifically, VEGFR-2 is a cell surface receptor for VEGFA, VEGFC, and VEGFD. It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeleton reorganization. Furthermore, VEGFR-2 mediates VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, which are essential processes in vasculogenesis and angiogenesis.

制备和贮存
保存方式

2 to 8 °C for 2 weeks under sterile conditions;

-20 °C for 3 months under sterile conditions; 

-80 °C for 24 months under sterile conditions.

Please avoid repeated freeze-thaw cycles.

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货号:
S0B0693-1mg
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