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Claturafenib
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产品介绍
产品介绍
产品信息
商品描述
Claturafenib (PF-07799933) is a brain-permeable, selective, all-mutant BRAF inhibitor with broad inhibitory effects on pERK levels in HT29 cells.Claturafenib has shown antitumor activity in preclinical studies in both BRAF V600- and non-V600-mutant cancers and can be used in combination with MEK inhibitors.
分子量
490.31
纯度
＞98%
可溶性
DMSO : 80 mg/mL (163.16 mM)
外观
White to light yellow Solid
背景
分子式
C18H15Cl2F2N5O3S
制备和贮存
保存方式
Store at -20℃ for three years（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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