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LY2090314
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产品介绍
产品介绍
产品信息
抗原名称
GSK-3α:1.5 nM, GSK-3β:0.9 nM
简单描述
LY2090314 是GSK-3抑制剂，抑制 GSK-3α (IC50:1.5 nM) 和 GSK-3β (IC50:0.9 nM)。
商品描述
LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
分子量
512.53
纯度
99.91%
性状
Solid
颜色
Yellow
In vitro(体外研究)
0
In vivo(体内研究)
LY2090314在实体瘤癌异种移植模型中提高了顺铂和卡铂的疗效。[1]
背景
别名
0
分子式
C28H25FN6O3
CAS号
603288-22-8
密度
1.55 g/cm3 (Predicted)
制备和贮存
溶解方法
DMSO: 93 mg/mL (181.45 mM), Sonication is recommended. Ethanol: 2 mg/mL (3.9 mM), Heating is recommended.
存储溶液
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
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