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ML-098
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产品介绍
产品介绍
产品信息
抗原名称
Rab7:77.6 nM (EC50)
简单描述
ML-098 (CID-7345532) 是 GTP 结合蛋白 Rab7的一种激活剂，EC50值为77.6nM。
商品描述
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
分子量
309.36
纯度
99.23%
In vitro(体外研究)
ML098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)[1].
背景
别名
CID-7345532
分子式
C19H19NO3
CAS号
878978-76-8
密度
1.17 g/cm3 (Predicted)
制备和贮存
溶解方法
DMSO: 50 mg/mL (161.62 mM), Sonication is recommended.
存储溶液
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
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