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Hu CD11c RR688 3.9 50ug
品牌： BD Pharmingen
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对比
咨询反应种属：
Human, Rhesus (Tested in Development)
实验应用：
Flow cytometry (Qualified)
产品介绍
产品介绍
产品信息
免疫原
Human monocytes and synovial cells
简单描述
The 3.9 monoclonal antibody specifically binds to CD11c, which is also known as Integrin alpha X (
α
X Integrin/ITGAX), or p150,95 Integrin alpha chain. CD11c is a ~150 kDa type I transmembrane glycoprotein. It is expressed on monocytes, macrophages, granulocytes, NK cells, dendritic cells, and subsets of B and T cells. It associates with CD18 (Integrin beta 2/
β
2 Integrin) to form the CD11c/CD18 complex, which is also known as p150,95 Integrin, or the Type 4 Complement Receptor (CR4). CD11c/CD18 binds fibrinogen and reportedly serves as a receptor for iC3b and ICAM-1/CD54. CD11c/CD18 functions as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium. The 3.9 monoclonal antibody crossreacts with CD11c expressed by Rhesus macaque leucocytes.
商品描述
3.9
The 3.9 monoclonal antibody specifically binds to CD11c, which is also known as Integrin alpha X (
α
X Integrin/ITGAX), or p150,95 Integrin alpha chain. CD11c is a ~150 kDa type I transmembrane glycoprotein. It is expressed on monocytes, macrophages, granulocytes, NK cells, dendritic cells, and subsets of B and T cells. It associates with CD18 (Integrin beta 2/
β
2 Integrin) to form the CD11c/CD18 complex, which is also known as p150,95 Integrin, or the Type 4 Complement Receptor (CR4). CD11c/CD18 binds fibrinogen and reportedly serves as a receptor for iC3b and ICAM-1/CD54. CD11c/CD18 functions as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium. The 3.9 monoclonal antibody crossreacts with CD11c expressed by Rhesus macaque leucocytes.
同种型
Mouse IgG1, κ
克隆号
克隆 3.9 (RUO)
浓度
0.2 mg/ml
产品详情
RR688
The BD Horizon RealRed™ 688 (RR688) Dye is part of the BD red family of dyes. It is a small organic fluorochrome with an excitation maximum (Ex Max) at 669 nm and an emission maximum (Em Max) at 688 nm. Driven by BD innovation, RR688 is designed for detection on spectral cytometers and to be excited by the Red laser (627–640 nm). Given its unique emission max, RR688 can be used on a spectral instrument in combination with APC and either R718 or Alexa Fluor™ 700. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
RR688
669 nm
688 nm
BD化合物表
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应用
实验应用
Flow cytometry (Qualified)
反应种属
Human, Rhesus (Tested in Development)
目标/特异性
CD11c (Integrin αX)
背景
别名
ITGAX; AlphaX Integrin; Axb2; Integrin alpha-X; CR4; SLEB6; p150,95 alpha
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
数据库链接
Entrez-Gene ID
3687
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