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产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Protein A

抗原名称
CD192

宿主
Mouse

同种型
IgG2a,k

克隆号
S-2971

浓度
0.2 mg/ml

性状
Liquid

缓冲体系
PBS, 1% BSA, 0.09% sodium azide

产品类型
Mouse mAb

应用
实验应用
FCM

反应种属
Hu

稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
IP
IHC-P
ICC
IF
ICFCM
FCM
5μl per million cells in 100μl volumemIHC
ChIP
背景
别名
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor (MCP-1-R); CMKBR2

背景
CD192, also called CCR2, is a 42 kDa seven-transmembrane G-protein-coupled receptor expressed mainly on monocytes, macrophages and basophils that binds the chemokines MCP-1 (CCL2), MCP-3 (CCL7) and MCP-4 (CCL13), triggers intracellular calcium flux and inhibition of adenylyl cyclase, thereby directing chemotaxis and bone marrow homeostasis, and has been implicated in inflammatory diseases such as rheumatoid arthritis, atherosclerosis and cancer as well as serving as an alternative HIV-1 coreceptor with CD4.

细胞定位
Cell membrane

制备和贮存
保存方式
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
数据库链接
Accession
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