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GSK-J4 hydrochloride
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产品介绍
产品介绍
产品信息
抗原名称
KDM6
商品描述
GSK-J4 hydrochloride is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively. GSK-J4 hydrochloride inhibits LPS-induced TNF-α production in human primary macrophages with an IC50 of 9 μM. GSK-J4 hydrochloride is a cell permeable proagent of GSK-J1.
分子量
453.97
纯度
≥98%
可溶性
Ethanol : 20 mg/mL (44.06 mM)
DMSO : 50 mg/mL (110.14 mM)
DMSO : 50 mg/mL (110.14 mM)
外观
Light yellow to yellow solid
背景
分子式
C24H27N5O2 • HCl
制备和贮存
保存方式
Store at -20℃ for three years（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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