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Invivo anti-Mouse CD8α Recombinant mAb
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对比
咨询纯度：
>95% (Determined by SDS-PAGE)
反应种属：
Ms
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
纯化方式
Protein G
抗原名称
CD8α
宿主
Rat
同种型
Rat IgG2a,k
克隆号
53-6.7
纯度
>95% (Determined by SDS-PAGE)
内毒素水平
<2EU/mg
浓度
5 mg/ml
性状
Liquid
缓冲体系
PBS pH7.4, containing no preservative
产品类型
Rat mAb
应用
实验应用
in vivo CD8+ T cell depletion
反应种属
Ms
稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
IP
IHC-P
ICC
IF
mIHC
ChIP
背景
别名
Lyt-2
背景
CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
细胞定位
Cell membrane
制备和贮存
保存方式
2 to 8 °C for 2 weeks under sterile conditions;
-20 °C for 3 months under sterile conditions;
-80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.
数据库链接
Accession
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