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nmt55/p54nrb Recombinant Rabbit mAb (S-1745-48)
品牌： STARTER
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对比
咨询反应种属：
Hu、Ms、Rt
来源宿主：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
纯化方式
Protein A
抗原名称
nmt55/p54nrb
宿主
Rabbit
免疫原
Synthetic Peptide
同种型
IgG
克隆号
S-1745-48
浓度
0.5 mg/ml
性状
Liquid
缓冲体系
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
产品类型
Recombinant mAb
应用
实验应用
WB、IHC-P、ICC
反应种属
Hu、Ms、Rt
稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
1:1000IP
IHC-P
1:1000ICC
1:500IF
mIHC
背景
别名
Non-POU domain-containing octamer-binding protein; NonO protein; 54 kDa nuclear RNA- and DNA-binding protein (p54(nrb); p54nrb); 55 kDa nuclear protein (NMT55); DNA-binding p52/p100 complex, 52 kDa subunit; NONO; NRB54
背景
p54nrb, also known as NONO, is a multifunctional nuclear protein that plays a role in various nuclear processes, including transcriptional control, RNA splicing and editing, and DNA unwinding and pairing. It is involved in the nuclear retention of defective RNAs and RNA transport, and its disruption can lead to expressional changes of tumorigenic genes and decreased stress tolerance, resulting in increased cell death susceptibility in human tumor cells. Additionally, p54nrb is multiphosphorylated during mitosis and interacts with the mitotic regulator Pin1, suggesting its involvement in cell cycle regulation.
细胞定位
Nucleus
制备和贮存
保存方式
12 months from date of receipt / reconstitution, -20 °C as supplied
数据库链接
Accession
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