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产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: a7 nicotinic acetylcholine receptor; acetylcholine receptor; acetylcholine receptor alpha 7 neural; alpha 7 neuronal nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha7 nicotinic receptor; alpha7-nAChR; bungarotoxin alpha; C holinergic receptor nicotinic alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); cholinergic receptor; cholinergic receptor, nicotinic alpha 7; cholinergic receptor, nicotinic, alpha 7 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 7; CHRFAM7A; CHRNA7-DR1; D-10; nAChR alpha7; neuronal acetylcholine receptor protein, alpha-7 chain; Neuronal acetylcholine receptor subunit alpha-7; neuronal nicotinic acetycholine receptor alpha 7; nicotinic receptor alpha 7 subunit
基因别名: Acra7; alpha7; BTX; CHRNA7; CHRNA7-2; nAchR; NACHRA7; NARAD
UniProt ID:(Human) P36544, (Rat) Q05941, (Mouse) P49582
Entrez Gene ID:(Human) 1139, (Rat) 25302, (Mouse) 11441
参考图片
Cell surface detection ofnAChR alpha 7 in live intact human THP-1 monocytic leukemia cells: - (black line) cells. (red) Cells + rabbit IgG isotype control-FITC. (green) Cells + Anti-Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular)-FITC Antibody (#ANC-007-F), (2.5 µg).
Cell surface detection ofnAChR alpha 7 in live intact mouse J774 macrophage cells: - (black line) cells. (red) Cells + rabbit IgG isotype control-FITC. (green) Cells + Anti-Nicotinic Acetylcholine Receptor alpha 7 (CHRNA7) (extracellular)-FITC Antibody (#ANC-007-F), (5 µg).