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产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel, activated in response to systemic osmotic pressure. Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The TRPV4 protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in the TRPV4 gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Diseases associated with TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; OTRPC4; Transient receptor potential cation channel subfamily V member 4; transient receptor potential cation channel, subfamily 5, member 4; TrpV4; Vanilloi; vanilloid receptor-related osmotically activated channel (Vroac); Vanilloid receptor-related osmotically-activated channel; VR-OAC
基因别名: Otrpc4; Trpv4; Vroac
UniProt ID:(Rat) Q9ERZ8
Entrez Gene ID:(Rat) 66026
参考图片
Western blot analysis of rat brain membranes: - 1. Guinea pig Anti-TRPV4 Antibody (#Acc-034-GP), (1:1500). 2. Guinea pig Anti-TRPV4 Antibody , preincubated with TRPV4 Blocking Peptide (#BLP-CC034).
Western blot analysis of rat DRG lysates: - 3. Guinea pig Anti-TRPV4 Antibody (#Acc-034-GP), (1:200). 4. Guinea pig Anti-TRPV4 Antibody , preincubated with TRPV4 Blocking Peptide (#BLP-CC034).