TAL1 ANTIBODY

品牌： Thermo

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产品介绍

产品信息

应用

建议稀释比

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酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

TAL1/3146

抗原

Recombinant human full-length TAL1 protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

TAL-1 is a basic helix-loop-helix transcription. It regulates differentiation and survival during hemopoiesis. TAL-1 is also implicated in the genesis of hemopoietic malignancies and it may play an important role in hemopoietic differentiation. It serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. TAL-1 is know to bind to the LIM domain containing protein Rhombotin-2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: bHLHa17; Class A basic helix-loop-helix protein 17; HGNC:11556; Stem cell protein; T-cell acute lymphocytic leukemia 1; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; TAL-1; tal-1 product

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基因别名: BHLHA17; SCL; tal-1; TAL1; TCL5

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UniProt ID:(Human) P17542

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Entrez Gene ID:(Human) 6886

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功能

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding enzyme binding histone deacetylase binding transcription regulatory region DNA binding protein heterodimerization activity E-box binding basic helix-loop-helix transcription factor

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