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KCNN3 (KCA2.3- SK3) (C-TERM) A

KCNN3 (KCA2.3- SK3) (C-TERM) A

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品牌: Thermo
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已发表文章

免疫印迹 (WB)

1:200
-
产品规格

种属反应

Human,Mouse,Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)KQIGSLESKLEHLTAS, corresponding to amino acid residues 659-674 of human KCNN3, Intracellular, C-terminal domain

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: KCa2.3; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; SK3; SKCa 3; SKCa3; small conductance calcium-activated potassium channel 3; Small conductance calcium-activated potassium channel protein 3; small-conductance Ca2+-activated K+ channel 3

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基因别名: hSK3; K3; KCa2.3; KCNN3; SK3; SKCA3

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参考图片

Western blot analysis of rat brain membranes: - 1. Anti-KCNN3 (KCa2.3, SK3) (C-term) Antibody (#APC-103), (1:200). 2. Anti-KCNN3 (KCa2.3, SK3) (C-term) Antibody , preincubated with KCNN3/KCa2.3 (C-term) Blocking Peptide (#BLP-PC103).

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货号:
APC-103-200UL
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200UL
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