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SLO BETA 2 (KCNMB2) ANTIBODY
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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: big potassium channel beta subunit 2; BK channel beta subunit 2; BK channel subunit beta-2; BKbeta2; calcium-activated potassium channel beta 2; Calcium-activated potassium channel subunit beta-2; Calcium-activated potassium channel, subfamily M subunit beta-2; Charybdotoxin receptor subunit beta-2; hbeta2; Hbeta3; hCG1646471; K(VCA)beta-2; large conductance calcium-activated potassium channel beta 2 subunit; large-conductance Ca2+-activated K+ channel beta2 subunit; Maxi K channel subunit beta-2; MaxiK channel beta 2 subunit; MaxiK channel beta-subunit 2; potassium channel subfamily M regulatory beta subunit 2; potassium large conductance calcium-activated channel, subfamily M, beta member 2; Rbeta3; Slo-beta-2; Slo-beta2
基因别名: Kcmb2; KCNMB2
UniProt ID:(Human) Q9Y691, (Rat) Q811Q0
Entrez Gene ID:(Human) 10242, (Rat) 294961
参考图片
Expression of KCNMB2in rat hippocampus - Immunohistochemical staining of rat hippocampus using Anti-slo beta 2 (KCNMB2) Antibody (#APC-034). A. KCNMB2appears in the pyramidal layer (green). B. Staining of interneurons with mouse Anti-parvalbumin (PV, red). C. Confocal merge of KCNMB2and PV demonstrates presence of KCNMB2also in PV (GABA containing) cells (orange).
Western blot analysisof rat kidney (lanes 1 and 3) and heart (lanes 2 and 4) membranes: - 1,2. Anti-slo beta 2 (KCNMB2) Antibody (#APC-034), (1:200).3,4. Anti-slo beta 2 (KCNMB2) Antibody , preincubated with slo beta 2/KCNMB2 Blocking Peptide (#BLP-PC034).