老带新
首页
MYOD1 (RHABDOMYOSARCOMA MARKER
MYOD1 (RHABDOMYOSARCOMA MARKER

MYOD1 (RHABDOMYOSARCOMA MARKER

分享
品牌： Thermo
用小程序，查商品更便捷
收藏
对比对比
咨询咨询
产品介绍
产品介绍
产品信息
应用
建议稀释比
已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent
-

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL
-

免疫细胞化学 (ICC/IF)

1-2 µg/mL
-

流式细胞分析 (Flow)

1-2 µg/10^6 cells
-
产品规格

种属反应

Chicken,Human,Mouse,Rat

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

SPM427

抗原

Recombinant MyoD of Mouse origin with an epitope mapping to amino acids 180-189.
查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: bHLHc1; Class C basic helix-loop-helix protein 1; Myf-3; Myoblast determination protein 1; Myoblast determination protein 1 homolog; MYOD1 homolog; myogenic factor 1; Myogenic factor 3; unnamed protein product

查看更多 收起

基因别名: AI503393; BHLHC1; CMD1; MYF3; MYOD; Myod-1; MYOD1; PUM

查看更多 收起

UniProt ID:(Human) P15172, (Chicken) P16075, (Mouse) P10085, (Rat) Q02346

查看更多 收起

Entrez Gene ID:(Human) 4654, (Chicken) 374048, (Mouse) 17927, (Rat) 337868

查看更多 收起

功能
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription coactivator activity protein binding transcription factor binding chromatin DNA binding ubiquitin protein ligase binding nuclear hormone receptor binding protein heterodimerization activity E-box binding RNA polymerase II transcription factor activity, sequence-specific DNA binding identical protein binding bHLH transcription factor binding protein dimerization activity promoter-specific chromatin binding DNA binding transcription factor activity, sequence-specific DNA binding enzyme binding sequence-specific DNA binding basic helix-loop-helix transcription factor
参与通路
regulation of alternative mRNA splicing, via spliceosome regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter protein phosphorylation muscle organ development myoblast fate determination skeletal muscle tissue development myoblast fusion cellular response to starvation myotube cell development myotube differentiation involved in skeletal muscle regeneration skeletal muscle cell differentiation muscle cell fate commitment positive regulation of skeletal muscle tissue regeneration regulation of RNA splicing skeletal muscle fiber adaptation histone H3 acetylation histone H4 acetylation positive regulation of myoblast differentiation positive regulation of transcription from RNA polymerase II promoter skeletal muscle fiber development positive regulation of skeletal muscle fiber development positive regulation of muscle cell differentiation cellular response to glucocorticoid stimulus cellular response to estradiol stimulus cellular response to oxygen levels positive regulation of myoblast fusion negative regulation of myoblast proliferation positive regulation of snRNA transcription by RNA polymerase II transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development myotube differentiation cell differentiation skeletal muscle tissue regeneration myoblast differentiation positive regulation of transcription, DNA-templated striated muscle cell differentiation cardiac muscle cell differentiation skeletal muscle atrophy response to muscle stretch

参考图片

Formalin-fixed, paraffin-embedded human Rhabdomyosarcoma stained with MyoD1 Mouse Monoclonal Antibody (SPM427).

声明 ：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。
货号：
4654-MSM1X-P0
一键复制
询价
20UG
选择数量
当前规格1件起购 
配送至
预计4-6周送达，快递: 免运费，若需干冰额外收费
询价 大包装询价