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产品详细信息
This antibody is predicted to work with Mouse and Rat.
靶标信息
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cAMP response element-binding protein CRE-BPa; cAMP-response element-binding protein A; CRE-BPa; CREB-5; Cyclic AMP-responsive element-binding protein 5
基因别名: CRE-BPA; CREB-5; CREB5; CREBPA
UniProt ID:(Human) Q02930
Entrez Gene ID:(Human) 9586
参考图片
Immunocytochemistry/Immunofluorescence analysis of PFA-fixed K562 cells using CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1) followed by goat anti-mouse IgG-CF488 (green); phalloidin counterstain (red)..
Western Blot analysis of HeLa cell lysate using CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1).
Flow Cytometry analysis of PFA-fixed K562 cells using CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).
Flow Cytometry analysis of PFA-fixed HeLa cells using CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).
Analysis of Protein Array containing more than 19,000 full-length human proteins CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
SDS-PAGE Analyis Purified CREB5, CRE-BPa Monoclonal Antibody (Product # 9586-MSM1-P1). Confirmation of Purity and Integrity of Antibody.