全部商品分类
下载产品说明书 下载SDS
用小程序，查商品更便捷
收藏
对比
咨询种属反应
宿主/亚型
分类
类型
抗原
偶联物
形式
浓度
纯化类型
保存液
内含物
保存条件
运输条件
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: leucine rich repeat neuronal 6A; leucine-rich repeat; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
基因别名: 4930471K13Rik; AV148400; LERN1; LINGO-1; LINGO1; LRRN6A; UNQ201; UNQ201/PRO227
UniProt ID:(Human) Q96FE5, (Mouse) Q9D1T0
Entrez Gene ID:(Human) 84894, (Rat) 315691, (Mouse) 235402
参考图片
Expression of LINGO-1 in rat brain and spinal cord - Immunohistochemical staining of perfusion-fixed frozen rat brain sections using Anti-LINGO-1 (extracellular) Antibody (#ANT-032), (1:400), followed by donkey- Anti-rabbit-Cy3. A. LINGO-1 staining (red) is detected in sections of rat substantia nigra, in nigral neurons (arrows). B. Staining of rat spinal cord shows LINGO-1 labeling in ventral horn neurons (arrows). Cell nuclei are stained with DAPI (blue).
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4)brain membranes: - 1,2. Anti-LINGO-1 (extracellular) Antibody (#ANT-032), (1:200).3,4. Anti-LINGO-1 (extracellular) Antibody , preincubated with LINGO-1 (extracellular) Blocking Peptide (#BLP-NT032).
Western blot analysis of human SH-SY5Y neuroblastoma cell line lysate: - 1. Anti-LINGO-1 (extracellular) Antibody (#ANT-032), (1:500). 2. Anti-LINGO-1 (extracellular) Antibody , preincubated with LINGO-1 (extracellular) Blocking Peptide (#BLP-NT032).