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产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor beta 2 neural; acetylcholine receptor, nicotinic, beta 2 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor subunit beta-2; neuronal nicotinic acetylcholine receptor beta 2
基因别名: [b]2-nAchR; Acrb-2; Acrb2; C030030P04Rik; CHRNB2; EFNL3; nAChRB2
UniProt ID:(Human) P17787, (Rat) P12390, (Mouse) Q9ERK7
Entrez Gene ID:(Human) 1141, (Rat) 54239, (Mouse) 11444
参考图片
Expression of nAChR beta 2 in rat PC12 cells - Cell surface detection of nAChR beta 2 in live intact rat pheochromocytoma PC12 cells. A. Cells were stained with Anti-Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (extracellular) Antibody (#ANC-012), (1:100), followed by goat Anti-rabbit-Alexa Fluor- 594 secondary Antibody (red). B. Cell nuclei were visualized using Hoechst 33342 (blue). C. Live view of the cells.
Western blot analysis of SH-SY5Y human neuroblastoma cell lysate (lanes 1 and 4) and rat (lanes 2 and 5) and mouse (lanes 3 and 6) brain lysate: - 1-3. Anti-Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (extracellular) Antibody (#ANC-012), (1:200).4-6. Anti-Nicotinic Acetylcholine Receptor beta 2 (CHRNB2) (extracellular) Antibody , preincubated with Nicotinic Acetylcholine Receptor beta 2/CHRNB2 (extracellular) Blocking Peptide (#BLP-NC012).