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产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein RIC-3; putative alpha7-nAChR chaperone; resistance to inhibitors of cholinesterase 3 homolog; resistance to inhibitors of cholinesterase 3-like protein; Resistant to inhibitor of cholinesterase 3
基因别名: AYST720; E130307J04Rik; PRO1385; RIC3; UNQ720/PRO1385
UniProt ID:(Human) Q7Z5B4, (Mouse) Q8BPM6
Entrez Gene ID:(Human) 79608, (Rat) 687147, (Mouse) 320360
参考图片
Expression of RIC-3 in mouseolfactory bulbandfornix - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-RIC3 Antibody (#ANC-020), (1:400), followed by goat- Anti-rabbit-AlexaFluor-488. A. RIC-3 staining in mouse olfactory bulb shows staining in the external plexiform layer (EPL) and in some glomeruli (G). Arrows point at glomeruli with RIC-3 positive core. B. RIC-3 staining in mouse fornix is detected in neuronal profiles (vertical arrows) and neuronal processes (horizontal arrow). Cell nuclei are stained with DAPI (blue).
Western blot analysis of mouse heart membranes (lanes 1 and 4), rat heart lysate (lanes 2 and 5) and rat brain lysate (lanes 3 and 6): - 1-3. Anti-RIC3 Antibody (#ANC-020), (1:200).4-6. Anti-RIC3 Antibody , preincubated with RIC3 Blocking Peptide (#BLP-NC020).
Western blot analysis of human SH-SY5Y neuroblastoma cell line lysate: - 1. Anti-RIC3 Antibody (#ANC-020), (1:200). 2. Anti-RIC3 Antibody , preincubated with RIC3 Blocking Peptide (#BLP-NC020).