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NMDAR2C (GRIN2C) (EXTRACELLULA
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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: GluN2C; GluRepsilon3; Glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor; Glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; glutamate receptor, ionotropic, NMDA2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NMDA glutamate receptor; NMDAR2C; NR2
基因别名: GluN2C; GRIN2C; NMDAR2C; NR2C
UniProt ID:(Human) Q14957, (Mouse) Q01098, (Rat) Q00961
Entrez Gene ID:(Human) 2905, (Mouse) 14813, (Rat) 24411
参考图片
Expression of NMDAR2C in rat pancreas - Immunohistochemical staining rat pancreas paraffin-embedded sections using Anti-NMDAR2C (GRIN2C) (extracellular) Antibody (#AGC-018), (1:100) followed by goat- Anti-rabbit-AlexaFluor-594 (red) secondary Antibody . Staining is present in endocrine cells of the Isles of Langerhans. Hoechst 33342 is used as the counterstain (blue).
Western blot analysis of mouse brain lysate: - 1. Anti-NMDAR2C (GRIN2C) (extracellular) Antibody (#AGC-018), (1:200). 2. Anti-NMDAR2C (GRIN2C) (extracellular) Antibody , preincubated with NMDAR2C/GRIN2C (extracellular) Blocking Peptide (#BLP-GC018).
Western blot analysis of rat brain membrane: - 1. Anti-NMDAR2C (GRIN2C) (extracellular) Antibody (#AGC-018), (1:200). 2. Anti-NMDAR2C (GRIN2C) (extracellular) Antibody , preincubated with NMDAR2C/GRIN2C (extracellular) Blocking Peptide (#BLP-GC018).