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产品介绍
产品介绍
产品信息
抗原名称
Moneky CCR6； Human CCR6；Human CCR7
商品描述
CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.
分子量
504.53
纯度
＞98%
可溶性
DMSO : 112.5 mg/mL (222.98 mM)
外观
White to off-white Solid
In vitro(体外研究)
CCR6 inhibitor 1 in human CCR6-transfected CHO cells showed a good correlation between Gi signal inhibitory activity and cell migration inhibitory activity, which could effectively inhibit CCR6-dependent cell migration and ERK phosphorylation increase in human primary cells[1].
背景
分子式
C24H23F3N4O3S
CAS号
2437547-04-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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