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Alexa Fluor® 647 Mouse Anti-Human CD243 Antibody (S-2907)
品牌： STARTER
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对比
咨询反应种属：
Hu
来源宿主：
Mouse
产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Protein A
抗原名称
CD243
宿主
Mouse
同种型
IgG2a,k
克隆号
S-2907
浓度
0.2 mg/ml
性状
Liquid
缓冲体系
PBS, 1% BSA, 0.3% Proclin 300
产品类型
Mouse mAb
应用
实验应用
FCM
反应种属
Hu
稀释度
ELISA
Sandwich ELISA
CLIA
Lateral Flow
Dot Blot
WB
IP
IHC-P
ICC
IF
ICFCM
FCM
5μl per million cells in 100μl volumemIHC
ChIP
背景
别名
ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; MDR1; PGY1; ABCB1
背景
CD243, also known as multidrug resistance protein 1 (MDR1) or P-glycoprotein (P-gp), is a 170 kDa transmembrane protein that belongs to the ATP-binding cassette (ABC) transporter family. It functions as an ATP-dependent efflux pump, transporting a wide range of lipophilic compounds, including anti-cancer drugs, out of cells. This protein is expressed on various cell types, such as B cells, T cells, and NK cells, but not on monocytes. CD243 plays a significant role in multidrug resistance in cancer therapy and is involved in the transport of molecules across cellular membranes.
细胞定位
Cytoplasm、Cell membrane
制备和贮存
保存方式
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
数据库链接
Accession
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