R&D Systems_Human BMP-2 DuoSet ELISA _优宁维(univ)在线
Human BMP-2 DuoSet ELISA
商品编码: DY355 品牌: R&D Systems 反应种属:
Human
Human
货号 规格 价格 库存 数量 操作
DY355 1Kit (for 15 Plates) ¥13187.00
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DY355-05 1Kit (for 5 Plates) ¥6752.00
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    产品信息
    产品形式
    96-well strip plate
    应用
    反应种属
    Human
    背景
    背景

    BMPs are secreted signaling molecules that comprise a subfamily of the TGF-beta superfamily and were originally identified as regulators of cartilage and bone formation. There are at least 20 structurally and functionally related BMPs, most of which play roles in embryogenesis and morphogenesis of various tissues and organs. Biologically active BMPs are usually homodimers containing a characteristic cysteine knot structure. Heterodimers, BMP-2/BMP-7 and BMP-4/BMP-7 have also been suggested to exist and function in vivo. They are more potent inducers of bone formation than their respective homodimers. In addition, heterodimers, but not homodimers, are ventral mesoderm inducers. Heterodimer activity may be mediated by a different or additional receptor subtype.

    Decapentaplegic (Dpp) is one of at least five TGF-beta superfamily ligands identified in the Drosophila genome. Dpp, a functional ortholog of mammalian BMP-2 and BMP-4, is a morphogen and plays an essential role in Drosophila development. Dpp regulates embryonic dorsal-ventral polarity and is required for gut morphogenesis and outgrowth and patterning of imaginal disks.

    别名
    BMP2; BMP-2; BMP-2A; BMP2ABone morphogenetic protein 2A; bone morphogenetic protein 2
    文献
    文献
    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    Human Articular Cartilage Progenitor Cells Are Responsive to Mechanical Stimulation and Adenoviral-Mediated Overexpression of Bone-Morphogenetic Protein 2.
    Authors: Neumann A, Gardner O, Williams R, Alini M, Archer C, Stoddart M
    PLoS ONE, 2015;10(8):e0136229.
    Species: Human
    Sample Type: Cell Culture Supernates

    Enhancement of bone regeneration by gene delivery of BMP2/Runx2 bicistronic vector into adipose-derived stromal cells.
    Authors: Lee SJ, Kang SW, Do HJ, Han I, Shin DA, Kim JH, Lee SH
    Biomaterials, 2010;31(21):5652-9.
    Species: Human
    Sample Type: Cell Culture Supernates

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