MAGI-3 (46)

mouse

抗-MAGI-3 抗体 46 是小鼠单克隆 IgG2a (kappa轻链)，MAGI-3抗体，规格为200 µg/ml 免疫human物种的MAGI-3的氨基酸194-298 推荐用于 mouse, rat 和 human 来源的MAGI-3 WB, IP, IF 和 IHC(P)检测 还可偶联琼脂糖 用于IP; 偶联HRP 用于WB, IHC(P) 和ELISA 关于如何获取MAGI-3 (46): sc-136471的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。 目前，我们还没有完成MAGI-3 抗体 (46)的首选二抗检测试剂的鉴定。这项工作正在进行中。 MAGI-3 Antibody (46) is a high quality monoclonal MAGI-3 antibody (also designated SLIPR antibody or MAGI3 antibody) suitable for the detection of the MAGI-3 protein of mouse, rat and human origin. MAGI-3 Antibody (46) is available as both the non-conjugated anti-MAGI-3 antibody form, as well as multiple conjugated forms of anti-MAGI-3 antibody, including agarose, HRP. The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK-related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3, contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique carboxy-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Replacement monoclonal antibody for: sc-11662.

IGG-免疫球蛋白G型抗体

260425;99470