Prostaglandin E2

1/2

Prostaglandin E2

品牌： Absin

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参数

分子式：

C₂₀H₃₂O₅

分子量：

352.47

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产品介绍

产品信息

抗原名称

EP2 Receptor,Human Endogenous Metabolite

商品描述

Prostaglandin E2 is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

分子量

352.47

纯度

≥98%

可溶性

DMSO ：70 mg/mL (198.59 mM)
Ethanol ：70 mg/mL (198.59 mM)
Water ：40 mg/mL (113.48 mM)

外观

White to off-white powder

In vitro(体外研究)

PGE2 shows inhibition of IL 2 production in the mixture of irradiated and nonirradiated T lymphocytes. PGE2 (0.1-10 μM) dose-dependently inhibits the production of IL 2. PGE2 acts during the inductive phase of activation of suppressor cells. Preincubation of T lymphocytes with PGE2 induces cells that suppress IL 2 production and PHA proliferation.

In vivo(体内研究)

PGE2 (0.3 μg/k, i.p.) significantly reduces the number of peritoneab macrophages undergoing phagocytosis of the methacrybate microbeads in rats. PGE2 (0.1 mg/min, i.a.) increases renal blood flow. PGE2 produces a biphasic change in renal vascular resistance, vasodilatation starts at 0.01 mg/min and is maximal at about 3 mg/min, while at the highest dose used (20 mg/min) PGE2 induces renal vasoconstriction.

背景

别名

地诺前列酮；前列腺素E2；Dinoprostone；PGE2

分子式

C₂₀H₃₂O₅

CAS号

363-24-6

制备和贮存

保存方式

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

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货号：

abs819421-5mg

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询价

5mg

50mg

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