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产品介绍
产品介绍
产品信息
商品描述
PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.
分子量
337.39
纯度
98%
可溶性
DMSO : 25 mg/mL (74.10 mM; Need ultrasonic)
外观
white to beige powder
In vitro(体外研究)
PSB-12062 shows similar potency in human, rat, and mouse species. PSB-12062 shows to be allosteric in nature with a 35-fold selectivity toward P2X4 versus P2X1, P2X2, P2X3, and P2X7. However, PSB-12062 is unable to completely block ATP-induced P2X4-mediated calcium influx even when used at high concentrations (>30 μM).
背景
分子式
C19H15NO3S
CAS号
55476-47-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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