PTEN (F-1)

mouse

PTEN抗体(F-1)是小鼠单克隆IgG1 κ, 在1篇文献中引用，规格为200 µg/ml 特异性抗原位于human物种的PTEN的N-terminus的氨基酸3-29之间 PTEN 抗体 (F-1) 推荐用于WB, IP, IF, IHC(P) 和 ELISA ，检测 mouse, rat, human 和 avian来源的PTEN; 也和以下物种反应，包括： 和 equine, canine, bovine, porcine and avian 抗-PTEN 抗体 (F-1) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统 关于如何获取PTEN (F-1): sc-393186的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。 m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 PTEN Antibody (F-1) for WB and IHC(P) 的首选应用二抗。这些试剂现在以套装形式提供PTEN Antibody (F-1)。 (见下方订购信息). As human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping of homozygous deletions on this chromosome led to the isolation of the PTEN gene, also designated MMAC1 (for mutated in multiple advanced cancers) and TEP1. This candidate tumor suppressor gene exhibits a high frequency of mutations in human glioblastomas and is also mutated in other cancers, including sporadic brain, breast, kidney and prostate cancers. PTEN has been associated with Cowden disease, an autosomal dominant cancer predisposition syndrome. The PTEN gene product is a putative protein tyrosine phosphatase that is localized to the cytoplasm and shares extensive homology with the cytoskeletal proteins tensin and auxilin. Gene transfer studies have indicated that the phosphatase domain of PTEN is essential for growth suppression of glioma cells.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USALI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Replacement monoclonal antibody for: sc-6818, sc-9145, sc-6817, sc-6817-R.

HumanPTEN

m, r, h

5728;19211