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PTPRN, ID (PTPRN, ICA3, ICA512, Receptor-type tyrosine-protein phosphatase-like N, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA-2)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
PTPRN protein
免疫原
PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-316 amino acids from the Central region of human PTPRN.
商品描述
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
形式
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
产品类型
Polyclonal
应用
实验应用
ELISA (EL/EIA), Western Blot (WB)
反应种属
Human
背景
别名
Anti -PTPRN, ID (PTPRN, ICA3, ICA512, Receptor-type tyrosine-protein phosphatase-like N, Islet cell antigen 512, Islet cell autoantigen 3, PTP IA-2)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
5798
UniProt ID
Q16849
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