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DHODH (E-8)

产品介绍
产品信息
宿主
mouse

简单描述
抗-DHODH 抗体 E-8 是小鼠单克隆 IgG2b κ,DHODH抗体, 在6篇文献中引用,规格为200 µg/mlraised against amino acids 1-300 mapping at the N-terminus of DHODH of human origin抗-DHODH 抗体 (E-8) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 DHODH抗-DHODH 抗体 (E-8) 可偶联 琼脂糖 用于 IP; HRP 用于 WB, IHC(P) 和 ELISA; 还可偶联 藻红蛋白 或者 FITC 用于 IF, IHC(P) 和 FCM还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统关于如何获取DHODH (E-8): sc-166348的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG2b BP-HRP 和 m-IgGκ BP-HRP 是 DHODH Antibody (E-8) for WB 首选应用二抗. 这些试剂现在以套形式提供 DHODH Antibody (E-8) (见下方订购信息).
查看产品引用文献(6) DHODH Antibody (E-8) is a high quality monoclonal DHODH antibody (also designated DHODH antibody) suitable for the detection of the DHODH protein of mouse, rat and human origin. DHODH Antibody (E-8) is available as both the non-conjugated anti-DHODH antibody form, as well as multiple conjugated forms of anti-DHODH antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DHODH (dihydroorotate dehydrogenase), also known as DHOdehase, is a 395 amino acid mitochondrial protein located on the outer surface of the inner mitochondrial membrane. It catalyzes the fourth enzymatic step in de novo pyrimidine biosynthesis. De novo pyrimidine synthesis is a critical metabolic pathway for nucleic acid synthesis and is a target for various cancer chemotherapy agents. Additionally, DHODH is functionally connected to the respiratory chain, delivering electrons to ubiquinone. DHODH contains a bipartite signal at the N-terminus that regulates passage into the mitochondrial inner membrane. The inhibition of COX (cytochrome c oxidase) by nitric oxide (NO) indirectly inhibits DHODH activity. The inhibition of D

克隆类别
Replacement monoclonal antibody for: sc-69377, sc-69379, sc-69380, sc-98570.

组成成分
IGG-免疫球蛋白G型抗体
