老带新
PZR (Myelin Protein Zero-like Protein 1, Protein Zero-related, MPZL1, UNQ849/PRO1787)

PZR (Myelin Protein Zero-like Protein 1, Protein Zero-related, MPZL1, UNQ849/PRO1787)

分享
品牌: MyBioSource
pdf 下载产品说明书
用小程序,查商品更便捷
收藏
对比对比
咨询咨询
反应种属:
Human
实验应用:
Western Blot (WB)
产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified Purified by Protein A affinity chromatography.
抗原名称
protein zero related protein
免疫原
Full length human MPZL1, aa1-269 (NP_003944.1).
商品描述
PZR (Protein zero related) is an immunoglobulin superfamily protein that specifically binds the tyrosine phosphatase SHP-2 through its intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs). PZR is phosphorylated by c-Src, c-Fyn, c-Lyn, Csk, and c-Abl. PP1, a Src family kinase inhibitor, inhibits PZR phosphorylation. There are three alternatively spliced isoforms designated as PZR, PZRa, and PZRb; both PZRa and PZRb lack ITIMs. PZR is a main receptor of ConA and has an important role in cell signaling via c-Src. PZR is expressed in many cell types and is localized to cell contacts and intracellular granules in BAECs and mesothelioma (REN) cells. Recently, PZR has been implicated as a cell adhesion protein that may be involved in SHP-2-dependent signaling at interendothelial cell contacts. Hypertyrosine phosphorylation of PZR was observed during embryogenesis in a mouse model of Noonan Syndrome.
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Polyclonal
应用
实验应用
Western Blot (WB)
反应种属
Human
背景
别名
Anti -PZR (Myelin Protein Zero-like Protein 1, Protein Zero-related, MPZL1, UNQ849/PRO1787)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
9019
UniProt ID
O95297 [Other Products]
声明 :本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。
货号:
MBS644809-0.1mg
一键复制
询价
0.1mg
选择数量
当前规格1件起购 
配送至
货期请咨询客服,快递: 免运费,若需干冰额外收费