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Rabbit anti-APC Polyclonal Antibody
Rabbit anti-APC Polyclonal Antibody
品牌： Absin
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对比
咨询分子量：
Predicted molecular weight: 312kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
反应种属：
Human;Mouse;Rat
产品介绍
产品介绍
产品信息
纯化方式
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
宿主
Rabbit
免疫原
A synthesized peptide derived from Human APC(Accession P25054), corresponding to amino acid residues Q2040-N2067.
商品描述
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
分子量
Predicted molecular weight: 312kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
克隆类别
Polyclonal Antibody
浓度
1mg/ml
应用
实验应用
WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:100-1:500, ICC: 1:100-1:500, ELISA: 1:20000-1:40000
反应种属
Human;Mouse;Rat
目标/特异性
APC Antibody detects endogenous levels of APC.
背景
别名
APC抗体
无
Expressed in a variety of tissues: brain, small intestine, colon, thymus, skeletal muscle, heart, prostate, lung, spleen, ovary, testis kidney, placenta, blood and liver (PubMed:21643010, PubMed:27217144). Isoform 1A: Very strongly expressed in brain but has relatively low expression levels in other tissues (PubMed:19527921, PubMed:21643010, PubMed:27217144). Isoform 1B: Predominant form in all tissues except for brain, including gastric mucosa and blood (PubMed:19527921, PubMed:21643010, PubMed:27217144).
细胞定位
Cytoskeleton;Cytosol;Nucleus;Plasma Membrane;
制备和贮存
存储溶液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
保存方式
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
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