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Rabbit anti-BMP2 Polyclonal Antibody
品牌： Absin
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对比
咨询分子量：
Predicted molecular weight: 45kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
反应种属：
Human, Mouse, Rat
产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
宿主
Rabbit
免疫原
A synthesized peptide derived from Human BMP2(Accession P12643), corresponding to amino acid residues G268-R289.
商品描述
Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation (1,2). BMPs are synthesized as precursor proteins that are processed by cleavage to produce mature proteins. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting in the translocation of Smad to the nucleus. BMP was also reported to activate MAPK pathways in some systems (3,4).
分子量
Predicted molecular weight: 45kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
克隆类别
Polyclonal Antibody
浓度
1mg/ml
应用
实验应用
WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
反应种属
Human, Mouse, Rat
目标/特异性
BMP2 Antibody detects endogenous levels of total BMP2.
背景
别名
BMP2抗体
翻译后修饰
Unmodified
无
Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
细胞定位
Extracellular region or secreted;Plasma Membrane;
制备和贮存
存储溶液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
保存方式
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
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