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Rabbit anti-HAMP Polyclonal Antibody
品牌： Absin
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对比
咨询分子量：
Predicted molecular weight: 9kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
反应种属：
Human, Mouse, Rat
产品介绍
产品介绍
产品信息
纯化方式
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
宿主
Rabbit
免疫原
A synthesized peptide derived from Human HAMP(Accession P81172), corresponding to amino acid residues L13-P39.
商品描述
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008]
分子量
Predicted molecular weight: 9kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
克隆类别
Polyclonal Antibody
浓度
1mg/ml
应用
实验应用
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:20000-1:40000
反应种属
Human, Mouse, Rat
目标/特异性
HAMP Antibody detects endogenous levels of total HAMP.
背景
别名
HAMP抗体
无
Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
细胞定位
Extracellular region or secreted;
制备和贮存
存储溶液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
保存方式
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
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