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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated

纯化方式
Protein A purified

宿主
Rabbit

免疫原
Recombinant human full-length Glypican 3 protein (Uniprot: P51654)

商品描述
200ug/ml of antibody purified by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-54468)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

分子量
67 kDa.

浓度
0.2 mg/ml

防腐剂
0.05% Sodium Azide

产品类型
Monoclonal

基因
GPC3

应用
实验应用
Flow Cytometry 1-2 ug/million cellsImmunocytochemistry/ Immunofluorescence 1-2 ug/mlImmunohistochemistry Immunohistochemistry-Paraffin 1-2 ug/ml

反应种属
Hu, RtSpecies Glossary

目标/特异性
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.

制备和贮存
保存方式
Store at 4C.
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