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产品介绍
产品信息
荧光素标记
Unconjugated

宿主
Rabbit

免疫原
This antibody was developed against Recombinant Protein corresponding to amino acids: ATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEY

简单描述
Novus Biologicals Rabbit Gephyrin/GPHN Antibody - BSA Free (NBP1-87875) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

同种型
IgG

克隆类别
Polyclonal

纯度
Immunogen affinity purified

防腐剂
0.02% Sodium Azide

基因
GPHN

应用
实验应用
WB, IHC

反应种属
Hu, Mu, Rt

稀释度
Immunohistochemistry 1:20 - 1:50Immunohistochemistry-Paraffin 1:20 - 1:50Western Blot 0.04-0.4 ug/ml
背景
别名
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

背景
The Gephyrin (GPHN) gene encodes a neuronal assembly protein that exists in isoform 1 (736 amino acids long, 79 kDA) or isoform 2 (769 amino acids in length, approximately 83 kDA). This protein anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton through high affinity binding to a receptor subunit domain and tublin dimers. The protein coded by GPHN is also necessary for molybdenum biosynthesis. The GPHN gene has been investigated in relation to many diseases such as leukemia, cervicitis, tuberculosis, alzheimer's disease, anorexia nervosa, huntington's disease, retinitis, and herpes zoster. The GPHN gene interacts with genes DYNLL1, PFN1, PRPF4, ENAH, and SLX4 to participate in pathways that regulate metabolism of vitamins and cofactors as well as molybdenum cofactor biosynthesis.

制备和贮存
存储溶液
PBS (pH 7.2) and 40% Glycerol

保存方式
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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