Rabbit anti-S100A9 Polyclonal Antibody

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Rabbit

A synthesized peptide derived from Human S100A9(Accession P06702), corresponding to amino acid residues T87-P114.

Predicted molecular weight: 13kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Polyclonal Antibody

1mg/ml

WB: 1:1000-3000, IHC: 1:200, ELISA: 1:20000-1:40000

Human, Mouse, Rat, Monkey

S100A9 Antibody detects endogenous levels of total S100A9.

S100A9抗体

Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn‘s disease, giant cell arteritis, cystic fibrosis, Sjogren‘s syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers.

Cytoskeleton;Cytosol;Extracellular region or secreted;Nucleus;Plasma Membrane;

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.