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Rabbit Polyclonal Rad17 Antibody
品牌： Novus
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对比
咨询纯度：
Immunogen affinity purified
反应种属：
Hu, Mu, Pm, Bv, Pm, Eq, Pm-Or, RM;The amino acid sequence used as immunogen is 85% homologous in Canine and Rat.
产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated
宿主
Rabbit
免疫原
This antibody was raised against RAD17
简单描述
Novus Biologicals Rabbit Rad17 Antibody (NBP2-27106) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
同种型
IgG
克隆类别
Polyclonal
纯度
Immunogen affinity purified
浓度
0.5 mg/ml
防腐剂
0.05% Sodium Azide
基因
RAD17
应用
实验应用
WB
反应种属
Hu, Mu, Pm, Bv, Pm, Eq, Pm-Or, RM;The amino acid sequence used as immunogen is 85% homologous in Canine and Rat.
稀释度
Western Blot 3-5ug/ml
背景
别名
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
背景
Rad17, also known as 'cell cycle checkpoint protein RAD17,' is a nuclear protein belonging to the Rad17/RAD24 family and necessary for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Rad17 is known to have a weak ATPase activity and is required for binding to chromatin and also participates in the recruitment of the RAD1-RAD9-HUS1 complex onto chromatin, and in CHEk1 activation. It may also serve as a sensor of DNA replication progression, and may be involved in homologous recombination. Rad17 is a part of a DNA-binding complex containing RFC2, RFC3, RFC4 and RFC5. Four isoforms have been reported by X-ray irradiation. Overexpression of this protein is seen in various cancer cell lines and in colon carcinoma.
制备和贮存
保存方式
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
数据库链接
UniProt ID
O75943()
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