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产品介绍
产品介绍
产品信息
荧光素标记
Unlabeled

宿主
Mouse

商品描述
Purified Mouse Monoclonal Antibody (Mab)

同种型
IgG1,κ

分子量
Predicted molecular weight: 37 kDa

克隆号
1281CT886.273.179.159

克隆类别
Monoclonal Antibody

应用
实验应用
WB: 1:2000

反应种属
Human, Mouse, Rat

目标/特异性
This RAD51 antibody is generated from a mouse immunized with a recombination protein from human.

背景
别名
RAD51抗体

研究领域
Crown Antibodies
翻译后修饰
Unmodified

细胞定位
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage (PubMed:20154705). DNA damage induces an increase in nuclear levels (PubMed:20154705). Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment (PubMed:23754376). Accumulated at sites of DNA damage in a SPIDR-dependent manner (PubMed:23509288). Recruited at sites of DNA damage in a MCM9-MCM8-dependent manner (PubMed:23401855) Colocalizes with ERCC5/XPG to nuclear foci in S phase (PubMed:26833090).

制备和贮存
存储溶液
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

保存方式
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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