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RNF212
品牌： Usbiological
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对比
咨询纯度：
Purified by immunoaffinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
免疫原
Recombinant human Probable E3 SUMO-protein ligase RNF212 V protein (aa1-297)
产品用途
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
简单描述
SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity).
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
应用
实验应用
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
推荐用量
Western Blot: 1:200-1000 Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Human
背景
别名
RING finger protein 212,RNF212
制备和贮存
保存方式
-20°C
数据库链接
SwissProt
Q495C1
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