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RNLS (Renalase, Monoamine Oxidase-C, MAO-C, C10orf59, FLJ11218)
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
renalase isoform 1
免疫原
Full length human C10orf59, aa1-342 (NP_001026879.1).
商品描述
Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. It is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity.
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Polyclonal
应用
实验应用
Western Blot (WB)
反应种属
Human
背景
别名
Anti -RNLS (Renalase, Monoamine Oxidase-C, MAO-C, C10orf59, FLJ11218)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
55328
UniProt ID
Q5VYX0
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